منابع مشابه
Funny channel-based pacemaking.
A a o ntroduction hat is the origin of normal cardiac pacemaking is an bviously intriguing question, given the fundamental role of acemaker activity in cardiac function. According to early tudies based on experiments in Purkinje fibers, pacemaking as first attributed to the decay of an outward current during iastolic depolarization. The process leading to generation f diastolic depolarization, ...
متن کاملArtificial Pacemaking and Sinus Rhythm.
The patients reported form part of a larger series of 60 patients with Stokes-Adams disease treated with artificial pacemakers, which is being reported in full elsewhere. The series contained 32 men between the ages of 39 and 81, and 28 women between 27 and 76. There was a bias towards the older age-groups with 53 per cent of the men and 62 per cent of the women being over 65 years. No patients...
متن کاملMathematical models of cardiac pacemaking function
*Correspondence: Aslak Tveito, Simula Research Laboratory, Martin Linges vei 17, Fornebu, P.O. Box 134, 1325, Oslo, Norway e-mail: [email protected] Over the past half century, there has been intense and fruitful interaction between experimental and computational investigations of cardiac function. This has led, for example, to more profound understanding of cardiac excitation-contraction couplin...
متن کاملSpecialised pacemaking cells in the rabbit urethra.
1. Collagenase dispersal of strips of rabbit urethra yielded, in addition to normal spindle-shaped smooth muscle cells, a small proportion of branched cells which resembled the interstitial cells of Cajal dispersed from canine colon. These were clearly distinguishable from smooth muscle in their appearance under the phase-contrast microscope, their immunohistochemistry and their ultrastructure....
متن کاملRobust pacemaking in substantia nigra dopaminergic neurons.
Dopaminergic neurons of the substantia nigra pars compacta are autonomous pacemakers. This activity is responsible for the sustained release of dopamine necessary for the proper functioning of target structures, such as the striatum. Somatodendritic L-type Ca2+ channels have long been viewed as important, if not necessary, for this activity. The studies reported here challenge this viewpoint. U...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2009
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.23.1_supplement.764.5